STPI researchers reviewed current Federal and non-governmental programs and projects that support research and development activities related to methane measurement and monitoring. Information was also collected information on current methane measurement research from Federal officials and researchers at organizations involved in the programs and projects reviewed. Based on input from these discussions and additional research, STPI found that the current portfolio of research indicates that integration of bottom-up inventory measurements and top-down atmospheric measurement approaches remains an important scientific topic that is actively being explored. Current scientific questions revolve around integrating multiple fields of atmospheric measurement and modeling, life-cycle assessment methodology, and integrating atmospheric measurement and life-cycle assessment processed based measurement approaches. Opportunities exist within the Federal government to build on existing research activities and to promote better coordination between agencies to support methane measurement research to aid mitigation approaches.