This report provides an overview of fiscal year 2019 activities at the IDA Science and Technology Policy Institute (STPI). STPI provides an independent, objective source of analyses for the White House Office of Science and Technology Policy and several other organizations in the Federal Government. The report provides highlights of STPI’s projects in the following categories: technology assessments and strategies; space technology and policy assessments; infrastructure assessments; economic analyses; Federal program and portfolio assessments; and agency program and portfolio assessments.